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MCE Tag

Cancer is the second leading cause of death globally and seriously threatens human health. A neoplasm and malignant tumor are other common names for cancer. Disruption of the normal regulation of cell-cycle progression and division lies at the heart of the events leading to cancer....

Antibody-drug conjugates (ADCs) are a new class of anti-tumor drugs formed by coupling a specific monoclonal antibody to a cytotoxic drug through a linker. ADCs usually consist of a fully-humanized monoclonal antibody (mAb), a cytotoxic drug and a suitable linker. The primary role of the antibody component...

Angiogenesis in Cancer Angiogenesis, the physiological process of generating new blood vessels from existing ones, is a hallmark of cancer. Blood vessels are required for tumor growth for nutrition, oxygen, and excretion of metabolic waste and carbon dioxide [1,2]. Main Pro-angiogenic Regulators The angiogenic switch indicates a point...

With the advent of cancer immunotherapy and checkpoint inhibitors, significant progress has been made in targeting the host's autoimmune response as an anticancer therapeutic intervention, transforming the oncology immunity and cancer treatment field. The unofficial classification of tumors into "cold tumors" and "hot tumors" based on tumor immune...

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