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MedChemExpress (MCE) provides an extensive collection of life-science biochemicals, including over 150,000+ bioactive compounds, dye reagents, peptides and natural compounds for research applications. CAS No.: 2117405-48-6 SW203668 TFA Research Area: Stearoyl-CoA desaturase (SCD)/Non-small Cell Lung Cancer (NSCLC) • An irreversible stearoyl-CoA desaturase (SCD) inhibitor with an IC50 of 54 nM. • Exhibits selective cytotoxicity...

MedChemExpress Streptavidin Magnetic Beads are developed using advanced nano-surface biotechnology to covalently immobilize recombinant neutral streptavidin as a uniform monolayer on superparamagnetic beads. This optimized surface design enables highly efficient separation and detection of biotinylated nucleic acids, antibodies, and other target molecules. The monolayer configuration keeps...

MCE IVT mRNA Platform MCE provides a one-stop solution covering sequence design and optimization, gene synthesis, plasmid preparation, template linearization, in vitro transcription (IVT), purification, and mRNA quality control. In addition, we offer a variety of capping options and nucleoside modification services. MCE mRNA Products • Reporter gene mRNAs...

  MedChemExpress (MCE) offers a wide range of high quality research chemicals and biochemicals including novel bioactive compounds, dye reagents, peptides and natural compounds for laboratory and scientific use. •  200,000+ bioactive molecules •  Target 1,500+ key proteins across 20+ signaling pathways •  Quality reports (LC/MS, NMR and HPLC)...

Inhibitor cocktails are mixtures of multiple chemical inhibitors designed to block specific biological pathways or cellular processes. They are widely used in research and drug discovery to investigate the effects of inhibiting enzymes, signaling pathways, or other molecular targets. Common inhibitor cocktails include protease inhibitors, kinase...

Nucleic acid drugs (NADs) can regulate the expression of specific genes by targeting genetic-level changes, treating genetic diseases, cancer, viral infections, and other complex conditions. MedChemExpress offers various types of oligonucleotides including ASOs, siRNA, miRNA, small activating RNA (saRNAs) and aptamers. These products have wide range of...

One Kit Next-Gen PCR Detection: YouSeq We’re proud to announce that YouSeq PCR detection kits are now available in our Q2UB E-Shop! YouSeq redefines next-generation PCR testing with its all-in-one kits, delivering comprehensive detection across a wide range of applications by leveraging advanced bioinformatics and lyophilized stability for...

MedChemExpress (MCE) provides an extensive collection of life-science biochemicals, including over 100,000 bioactive compounds, dye reagents, peptides and natural compounds for research applications. CAS No.: 2980682-00-4 RP-1664 Research Area: Polo-like Kinase (PLK)/Breast Cancer/Neuroblastoma • A selective and orally active PLK4 inhibitor with an IC50 of 3 nM. • Disrupts centriole biogenesis in...

The Critical Role of Protein-Protein Interactions (PPIs) PPIs serve as fundamental regulatory events of many cellular processes, including signal transduction, proliferation, and apoptosis. With an estimated 650,000 PPIs in humans[1], these interactions form intricate networks that govern protein function. Dysregulated PPIs are implicated in diseases such as...