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[MCE] Target Protein for ADCs

[MCE] Target Protein for ADCs

Antibody-drug conjugates (ADCs) are a new class of anti-tumor drugs formed by coupling a specific monoclonal antibody to a cytotoxic drug through a linker. ADCs usually consist of a fully-humanized monoclonal antibody (mAb), a cytotoxic drug and a suitable linker. The primary role of the antibody component in ADCs is to bind to the specific target antigens on the surface of tumor cells, bringing the attached cytotoxic payload to the target cells.

MCE offers a wide range of high-quality target proteins to meet
the needs of ADCs development!

Cat. No.  ADC Target Proteins
HY-P74895 HER2/CD340
HY-P70616 Nectin-4
HY-P70323 HER3
HY-P71387 TROP-2
Cat. No.  ADC Target Proteins
HY-P72990 EGFR
HY-P7656 BCMA/TNFRSF17
HY-P73605 TIM-1/KIM-1/HAVCR
HY-P7787 Coagulation Factor III/CD142

 

Features:

• Hot ADC targets, such as HER2, Nectin-4.
• Variable Species: Human, Mouse, Cynomolgus, Rat, etc.
• High Purity: Tested by SDS-PAGE & HPLC.
• Superior Biological Activity: Validated by relevant in vitro or in vivo assays.
• Excellent Lot-to-Lot Consistency: Confirmed by Lot-to-Lot data.

Applications:

Antibody screening, Cross-reactivity, in vivo or in vitro regulation mechanism
study, QC.

MedChemExpress — Master of Bioactive Molecules
• MCE offers 10,000+ Recombinant Proteins.