eTOPIX New Sensitive ELISA Kits for Metabolic Diseases Research

29 Jan eTOPIX New Sensitive ELISA Kits for Metabolic Diseases Research

The “Hunger Factor” ACBP
A NEW & Sensitive Biomarker
for Obesity Research

Recent studies show that Acyl-CoA-binding Protein [ACBP] levels correlate with human body mass index (BMI). Increasing ACBP levels in mice trigger lipogenesis, food intake and weight gain and neutralization of ACBP increases lipolysis, reduces food intake post-starvation and causes weight loss in mice.

Obese patients exhibit elevated plasma levels of ACBP, while a reduction in the ACBP mRNA and ACBP plasma concentration is observed in these patients after a substantial weight loss. ACBP might be useful for the prevention or treatment of obesity and metabolic syndrome diseases.

NEW & Sensitive Assay
Acyl-CoA-binding Protein (human) ELISA Kit

AdipoGen Life Sciences‘ Acyl-CoA-binding Protein (human) ELISA Kit (Prod. No. AG-45B-0019) is a sensitive (30pg/ml) colorimetric sandwich immunoassay that detects human ACBP in serum, plasma and cell culture supernatant. It does not detect mouse ACBP.  

Figure: Secretion of human ACBP during induction of autophagy is measured using the Acyl-CoA-binding Protein (human) ELISA Kit (Prod. No. AG-45B-0019). Method: Human embryonic kidney (HEK 293) (A) and B lymphoblast SKW 6.4 (B) cell lines are treated for 24 hours with different concentrations of the autophagy inducer Everolimus (Prod. No. AG-CN2-0520). Supernatants are collected, diluted and tested using the Acyl-CoA-binding Protein (human) ELISA Kit (Prod. No. AG-45B-0019).

Related other ACBP Reagents!

Other STANDARD ELISAs for Metabolic Diseases Research!

Download the Obesity & Diabetes Research Brochure

Includes:

• Obesity-related ELISA Kits, Antibodies & Proteins
• IL-33 and Adipose Tissue Homeostasis
• Immunometabolism: Small Molecules Modulators
• Obesity & Angiogenesis: Potent ANG-2 Blocking MAb
• Browning & Thermogenesis Regulators
• Myokines – Asprosin – IL-6 – Irisin
• Small Molecule Modulators