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Protein phosphorylation is one of the most common and important post-translational modifications, and it regulates a variety of cellular signaling pathways. Protein kinases regulate protein phosphorylation by catalyzing the transfer of the terminal phosphate group (PO4) of ATP to the hydroxyl group of an amino...
The CD40L (human) ELISA Kit (Prod. No. AG-45B-0018) from Adipogen Life Sciences is a sandwich ELISA for specific quantitative determination of human soluble CD40L in serum, plasma and cell culture supernatants. This ELISA Kit shows a very high specificity and sensitivity (20pg/ml). 𝐑𝐞𝐪𝐮𝐞𝐬𝐭 𝐄𝐋𝐈𝐒𝐀 𝐊𝐢𝐭 𝐦𝐚𝐧𝐮𝐚𝐥...
ImmunoChemistry Technologies is excited to announce we now offer Immunohistochemistry (IHC) reagents! IHC is the method for localizing specific antigens in tissue or cells using antibodies, enzyme conjugates and substrate-chromogens. The antigen-antibody reaction can be evidenced with an optical microscope. The antibodies can be polyclonal or...
Inflammasomes − Caspase-1 Activation Scaffolds An inflammasome represents a high molecular weight complex that activates inflammatory caspases and activates cytokines of the IL-1 family. Several inflammasomes have been described and were so far defined by the NLR protein that they contain - the NLRP1 (NALP1) inflammasome,...
Bio.etc Brand Ambassador Program [B.A.P] Program Period: 15 Aug 2023 - 31 Oct 2023 We are excited to announce the official launch of Bio.etc’s Brand Ambassador Program [B.A.P]! As a Brand Ambassador (BA), you will become an integral part of our family to refer your favourite brands...
Apoptosis is programmed cell death, and abnormal apoptosis can lead to the development of diseases such as cancer, neurological disorders and autoimmune diseases[1]. Two main apoptosis pathways: Intrinsic Pathway The intrinsic pathway, also known as the Bcl-2 regulatory or mitochondrial pathway (Figure 1), is regulated by Bcl-2 family proteins, including pro-apoptotic proteins (Bid, Bax, Bak) and anti-apoptotic...
Eliminate interference and nonspecific background noise associated with antibody-coated ELISA formats and sandwich ELISAs. SynBlock ELISA Blocking Buffer provides superior background-blocking performance without the use of conventional cross-reactive protein additives. SynBlock ELISA Blocking Buffer is a novel non-protein blocking formulation designed to eliminate interference and nonspecific...
Read recent publications from researchers around the world for June 2023: Sutton, MS;Pletnev, S;Callahan, V;Ko, S;Tsybovsky, Y;Bylund, T;Casner, RG;Cerutti, G;Gardner, CL;Guirguis, V;Verardi, R;Zhang, B;Ambrozak, D;Beddall, M;Lei, H;Yang, ES;Liu, T;Henry, AR;Rawi, R;Schön, A;Schramm, CA;Shen, CH;Shi, W;Stephens, T;Yang, Y;Florez, MB;Ledgerwood, JE;Burke, CW;Shapiro, L;Fox, JM;Kwong, PD;Roederer, M. Vaccine elicitation and...
Organoids are three-dimensional (3D) miniature structures cultured using human pluripotent stem cells (hPSCs) or adult stem cells (AdSCs). Compared with traditional 2D cell culture, organoids can closelymimic the cellular heterogeneity, structure, and function of the original organ and are widely used in drug development, precision...
Cell fractionation is the gateway to understanding the properties and functions of numerous cellular components. Fractionation involves disrupting the cell mechanically or chemically, followed by centrifuging the lysate to isolate fractions populated by organelles and cell membrane fragments by size and density. Subsequent analysis reveals...
